Mancini would fuck him up. I have no doubt. Mancini didnt have the one shot power of Maidana, but he was better than Maidana in every other way possible. Assuming he moves up 140 while he's still in his prime, he mugs Conman and stops him late.
Hmm... when you mention that part, it makes me reconsider my initial reaction. I was going to say, that I can easily see Khan employing and improving on what Camacho did (as sorry of a fight as that was), but I guess it's a different story with a prime Mancini.
