I think Inoue - and prime Donaire, who was definitely better than Inoue IMO - stops both brothers. I think Inoue probably lines him up for a punch Orlando can't take at some point. If he fight aggressively, then I'm sure. If Orlando circles and uses his footwork to move in-and-out, countering. I think Inoue catches him and finishes him. Gaby's style seems to be worse for Inoue.
The Canizales brothers had steel chins, if nothing else. I think Donaire beats Orlando, but via decision. There's only 3 bantamweights I would take to stop Orlando, and they should be obvious: Jofre, Zarate, Olivares.