The 140 Ortiz vs the 'lightweight' Shane. The static from Ortiz' brain power frizzes Shane's afro like a van der graff generator.
I'd take Mosley. Not only based on his size. His handspeed, and toughness would be highly problematic for Ortiz as well. And Shane had the firepower to damage Ortiz. I cant really say the opposite is true.
I'd say Ortiz's extreme advantage in intelligence and versatility is more than enough to offset Mosley's advantage in speed and power... Ortiz was light years more skilled than Mosley