Griffith was able to out-muscle Tiger, can he out-muscle a guy who would come into the ring at 180 lbs. in Canelo and win?
Prime Griffith wins a wide decision at 154. I think Griffith wins at 160 too, but Canelo has a real case there.
Canelo wouldn't have had the stamina/workrate or world class experience to win down at 154 IMO. 160 could be interesting, though I'd probably still give the edge to Griffith's all-around speed and versatility.