I don't think Simon ever got hurt. So he's just as busy as Williams and he hits harder and he's a weight class bigger. Since Williams beat Margarito, maybe he could beat Simon, but I think a pretty clear win for Simon is the best guess.
That's the biggest factor for me. And since I don't do P4P mythicals, I'd take Simon by decision in this one.
he got hurt by rodney jones, who was a lanky slick southpaw. but then again, simon was supposedly sick going into that fight. wayne alexander hurt him too, but he was a sick puncher.
Though at this point I favor Simon, he had much difficulty with southpaws. The bouts with Rodney Jones and Wright stand out. Both were decisions that could have gone either way.
Wright and Jones were five times as slick as Williams could ever hope to be. Simon is way too strong AND active. He beats Williams up.