Are we talking about a prime Tszyu or if they fought 2 years ago? A prime Tszyu at 140 would stop Cotto within 6 rounds, no doubt in my mind. Had they fought 2 years ago theres a still a legit chance Kostya might have iced him early seeing as what Torres did, but if he didnt get him early Cotto would have came on strong late and made Tszyu quit.
Tszyu would have iced within 5 rounds. Kostya may not hit as hard as Torres with one shot but he was quicker and a more clinical finisher. Kostya woulda won. Cotto however, would beat the Tszyu that lost to Hatton via late rounds stoppage.